Pfizer is whacking about 100 drug development programs out of a pipeline swollen by its merger with Wyeth. And Reuters reports that the bulk of the remaining 500 programs focus on six key areas: oncology, pain, inflammation, Alzheimer's disease, psychoses and diabetes.
Even after the culling process, though, Pfizer will have significantly boosted its work on vaccines and biotech drugs, a key reason for the merger. The move to quickly slim down the R&D side has led to some dramatic moves over the past three months. Pfizer is determined to mesh the two big organizations together in record time.
"The programs we culled in this first piece, either there was overlap between the portfolios or we had a piece of scientific information" that led to discontinuations, said Pfizer's Martin Mackay. And the winnowing process isn't complete. "We will continue to prioritize the portfolio," Mackay added.
Most of the programs dropped from the combined pipeline were in early-stage testing, with only three in Phase II. The three mid-stage drug programs were focused on diabetes, pain and thrombosis. And Pfizer plans to sell or out-license what it no longer wants to keep.
- here's the
Reuters piece
- here's the
AP report
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