Lyrica in depression
This is a discussion on Lyrica in depression within the Managed Care Issues for Oral Drugs forum, part of the Managed Care Drug Coverage category; I have been seeing quite a few prior authorization requests for Lyrica to treat depression. Are there any trials supporting ...
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02-21-2008, 07:30 PM
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Lyrica in depression
I have been seeing quite a few prior authorization requests for Lyrica to treat depression. Are there any trials supporting the use of Lyrica in depression?
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02-22-2008, 06:45 PM
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Re: Lyrica in depression
Though pregabalin has been shown effective in general anxiety disorder, only one recent case study notes the possible effectiveness of pregabalin in depression:
Showraki M. Pregabalin in the treatment of depression. Journal of Psychopharmacology. 2007;8:883-4. In addition, one review article suggests that antiepileptics may vary in their mood stabilizing and anxiolytic properties. Authors state that “Carbamazepine, valproate, lamotrigine, and oxcarbazepine appear to have mood stabilizing properties while gabapentin, pregabalin, and tiagabine have anxiolytic benefits:” Ettinger AB and Argoff CE. Use of antiepileptic drugs for nonepileptic conditions: psychiatric disorders and chronic pain. Neurotherapeutics. 2007;1:75-83. Last edited by diana.papshev : 02-28-2008 at 09:59 AM.
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