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View Full Version : Updates from the Technology Assessment Authorities


  1. TA227: Lung cancer (non-small-cell, advanced or metastatic maintenance treatment) - erlotinib (monotherapy)
  2. TA226: Lymphoma (follicular non-Hodgkin's) - rituximab
  3. TA225: Rheumatoid arthritis (after the failure of previous anti-rheumatic drugs) - golimumab
  4. TA223: Peripheral arterial disease - cilostazol, naftidrofyryl oxalate, pentoxifylline and inositol nicotinate
  5. TA220: Psoriatic arthritis - golimumab
  6. TA222: Ovarian cancer (relapsed) - trabectedin
  7. TA221: Thrombocytopenic purpura - romiplostim
  8. TA219: Everolimus for the second-line treatment of advanced renal cell carcinoma
  9. TA217: Alzheimer's disease - donepezil, galantamine, rivastigmine and memantine
  10. TA214: Breast cancer - bevacizumab (in combination with a taxane)
  11. : Renal cell carcinoma (first line metastatic) - pazopanib
  12. TA215: Renal cell carcinoma (first line metastatic) - pazopanib
  13. TA216: Leukaemia (lymphocytic) - bendamustine
  14. Schizophrenia - aripiprazole
  15. Project: SWITCH - Randomised- controlled trial of switching to alternative tumour necrosis factor-blocking drugs or abat
  16. TA212: Colorectal cancer (metastatic) - bevacizumab
  17. TA211: Constipation (women) - prucalopride
  18. TA210: Clopidogrel and modified-release dipyridamole for the prevention of occlusive vascular events (Review of TA90)
  19. Gastrointestinal stromal tumours (unresectable/metastatic) - imatinib
  20. TA208: Gastric cancer (HER2-positive metastatic) - trastuzumab
  21. TA205: Thrombocytopenic purpura - eltrombopag
  22. TA203: Liraglutide for the treatment of type 2 diabetes mellitus
  23. Osteoporotic fractures - denosumab
  24. TA201: Asthma (in children) - omalizumab
  25. TA202: Chronic lymphocytic leukaemia - ofatumumab
  26. TA200: Hepatitis C - peginterferon alfa and ribavirin
  27. TA196: Gastrointestinal stromal tumours - imatinib (adjuvant)
  28. TA197: Atrial fibrillation - dronedarone
  29. TA199: Psoriatic arthritis - etanercept, infliximab and adalimumab
  30. TA198: Rheumatoid arthritis - tocilizumab
  31. TA192: Lung cancer (non-small-cell, first line) - gefitinib
  32. TA194: Bone loss (therapy-induced) in non-metastatic prostate cancer - denosumab (terminated appraisal)
  33. TA191: Gastric cancer (advanced) - capecitabine
  34. TA193: Leukaemia (chronic lymphocytic, relapsed) - rituximab
  35. TA190: Lung cancer (non-small-cell) - pemetrexed (maintenance)
  36. TA26: Lung cancer - docetaxel, paclitaxel, gemcitabine and vinorelbine (replaced by CG24 Lung cancer)
  37. : Hepatocellular carcinoma (advanced and metastatic) - sorafenib (first line)
  38. TA188: Human growth hormone (somatropin) for the treatment of growth failure in children (review)
  39. TA187: Crohn's disease - infliximab (review) and adalimumab (review of TA40)
  40. TA141: Rheumatoid arthritis (refractory) - abatacept
  41. TA140: Ulcerative colitis (subacute manifestations) - infliximab
  42. TA143: Ankylosing spondylitis - adalimumab, etanercept and infliximab
  43. TA142: Anaemia (cancer-treatment induced) - erythropoietin (alpha and beta) and darbepoetin
  44. TA147: Breast cancer (advanced & metastatic) - bevacizumab (terminated appraisal)
  45. TA148: Lung cancer (non-small-cell) - bevacizumab (terminated appraisal)
  46. TA149: Glioma (recurrent) - carmustine implants (terminated appraisal)
  47. TA150: Colorectal cancer (metastatic) - cetuximab (terminated appraisal)
  48. TA146: Psoriasis - adalimumab
  49. TA145: Head and neck cancer - cetuximab
  50. TA151: Diabetes - insulin pump therapy
  51. TA138: Asthma (in adults) - corticosteroids
  52. TA137: Lymphoma (follicular non-Hodgkin's) - rituximab
  53. TA124: Lung cancer (non-small-cell) - pemetrexed
  54. TA126: Rheumatoid arthritis (refractory) - rituximab
  55. TA111: Alzheimer's disease - donepezil, galantamine, rivastigmine (review) and memantine
  56. TA130: Rheumatoid arthritis - adalimumab, etanercept and infliximab
  57. TA129: Multiple myeloma - bortezomib
  58. TA125: Psoriatic arthritis (moderate to severe) - adalimumab
  59. TA132: Hypercholesterolaemia - ezetimibe
  60. TA133: Asthma (uncontrolled) - omalizumab
  61. TA131: Asthma (in children) - corticosteroids
  62. TA134: Psoriasis - infliximab
  63. TA135: Mesothelioma - pemetrexed disodium
  64. TA153: Hepatitis B - entecavir
  65. TA154: Hepatitis B - telbivudine
  66. TA155: Macular degeneration (age-related) - ranibizumab and pegaptanib
  67. TA177: Eczema (chronic) - alitretinoin
  68. TA178: Renal cell carcinoma
  69. TA176: Colorectal cancer (first line) - cetuximab
  70. TA179: Gastrointestinal stromal tumours - sunitinib
  71. TA180: Psoriasis - ustekinumab
  72. TA182: Acute coronary syndrome - prasugrel
  73. TA183: Cervical cancer (recurrent) - topotecan
  74. TA184: Lung cancer (small-cell) - topotecan
  75. TA185: Soft tissue sarcoma - trabectedin
  76. TA186: Rheumatoid arthritis - certolizumab pegol
  77. TA173: Hepatitis B - tenofovir disoproxil fumarate
  78. TA174: Leukaemia (chronic lymphocytic, first line) - rituximab
  79. TA175: Lung cancer (non-small-cell, second line) - gefitinib (terminated appraisal)
  80. TA158: Influenza (prophylaxis) - amantadine, oseltamivir and zanamivir
  81. TA160: Osteoporosis - primary prevention
  82. TA161: Osteoporosis - secondary prevention including strontium ranelate
  83. TA162: Lung cancer (non-small-cell) - erlotinib
  84. TA163: Ulcerative colitis (acute exacerbations) - infliximab
  85. TA164: Hyperuricaemia - febuxostat
  86. TA168: Influenza - zanamivir, amantadine and oseltamivir (review)
  87. TA169: Renal cell carcinoma - sunitinib
  88. TA171: Multiple myeloma - lenalidomide
  89. TA172: Head and neck cancer (squamous cell carcinoma) - cetuximab
  90. TA181: Lung cancer (non-small cell, first line treatment) - pemetrexed
  91. TA32: Multiple sclerosis - beta interferon and glatiramer acetate
  92. TA55: Ovarian cancer - paclitaxel (review)
  93. TA61: Colorectal cancer - capecitabine and tegafur uracil
  94. TA62: Breast cancer - capecitabine (replaced by CG81)
  95. TA64: Growth hormone deficiency (adults) - human growth hormone
  96. TA65: Non-Hodgkin's lymphoma - rituximab
  97. TA67: Flu prevention - amantadine and oseltamivir (replaced by TA158)
  98. TA68: Macular degeneration (age-related) - photodynamic therapy
  99. TA70: Leukaemia (chronic myeloid) - imatinib
  100. TA75: Hepatitis C - pegylated interferons, ribavirin and alfa interferon
  101. TA79: Epilepsy (children) - newer drugs
  102. TA80: Acute coronary syndromes - clopidogrel
  103. TA54: Breast cancer - vinorelbine (replaced by CG81)
  104. TA53: Diabetes (types 1 and 2) - long acting insulin analogues
  105. TA29: Leukaemia (lymphocytic) - fludarabine
  106. TA36: Rheumatoid arthritis - etanercept and infliximab (Partially replaced by TA130)
  107. TA47: Acute coronary syndromes - glycoprotein IIb/IIIa inhibitors (review)
  108. TA25: Pancreatic cancer - gemcitabine
  109. TA20: Motor neurone disease - riluzole
  110. TA23: Brain cancer - temozolomide
  111. TA43: Schizophrenia - atypical antipsychotics (replaced by CG82)
  112. TA30: Breast cancer - taxanes (review)(replaced by CG81)
  113. TA34: Breast cancer - trastuzumab
  114. TA40: Crohn's disease - infliximab
  115. TA35: Arthritis (juvenile idiopathic) - etanercept
  116. TA42: Growth hormone deficiency (children) - human growth hormone
  117. TA82: Atopic dermatitis (eczema) - pimecrolimus and tacrolimus
  118. TA81: Atopic dermatitis (eczema) - topical steroids
  119. TA86: Gastro-intestinal stromal tumours (GIST) - imatinib
  120. TA108: Breast cancer (early) - paclitaxel
  121. TA110: Follicular lymphoma - rituximab
  122. TA112: Breast cancer (early) - hormonal treatments
  123. TA113: Diabetes (type 1 and 2) - inhaled insulin
  124. TA115: Drug misuse - naltrexone
  125. TA114: Drug misuse - methadone and buprenorphine
  126. TA117: Hyperparathyroidism - cinacalcet
  127. TA116: Breast cancer - gemcitabine
  128. TA118: Colorectal cancer (metastatic) - bevacizumab & cetuximab
  129. TA119: Leukaemia (lymphocytic) - fludarabine
  130. TA121: Glioma (newly diagnosed and high grade) - carmustine implants and temozolomide
  131. TA109: Breast cancer (early) - docetaxel
  132. TA106: Hepatitis C - peginterferon alfa and ribavirin
  133. TA107: Breast cancer (early) - trastuzumab
  134. TA91: Ovarian cancer (advanced) - paclitaxel, pegylated liposomal doxorubicin hydrochloride and topotecan (review)
  135. TA90: Vascular disease - clopidogrel and dipyridamole
  136. TA93: Colorectal cancer (advanced) - irinotecan, oxaliplatin and raltitrexed (review)
  137. TA94: Cardiovascular disease - statins
  138. TA96: Hepatitis B (chronic) - adefovir dipivoxil and pegylated interferon alpha-2a
  139. TA98: Attention deficit hyperactivity disorder (ADHD) - methylphenidate, atomoxetine and dexamfetamine (review)
  140. TA100: Colon cancer (adjuvant) - capecitabine and oxaliplatin
  141. TA99: Renal transplantation - immunosuppressive regimens for children and adolescents
  142. TA101: Prostate cancer (hormone-refractory) - docetaxel
  143. TA103: Psoriasis - efalizumab and etanercept
  144. TA104: Psoriatic arthritis - etanercept and infliximab
  145. TA127: Multiple sclerosis - natalizumab
  146. TA185: Soft tissue sarcoma - trabectedin
  147. TA186: Rheumatoid arthritis - certolizumab pegol
  148. TA184: Lung cancer (small-cell) - topotecan
  149. TA182: Acute coronary syndrome - prasugrel
  150. TA183: Cervical cancer (recurrent) - topotecan
  151. TA180: Psoriasis - ustekinumab
  152. TA181: Lung cancer (non-small cell, first line treatment) - pemetrexed
  153. TA179: Gastrointestinal stromal tumours - sunitinib
  154. TA178: Renal cell carcinoma
  155. TA177: Eczema (chronic) - alitretinoin
  156. TA176: Colorectal cancer (first line) - cetuximab
  157. National Quality Forum endorses 18 medication management measures
  158. Publication: Volume 13, number 34 (Ara). Study found that rosuvastatin 40 mg/day is the most effective treatment in term
  159. Publication: Volume 13, number 35 (Jones). Study found that both adefovir dipivoxil and pegylated interferon alpha are b
  160. TA173: Hepatitis B - tenofovir disoproxil fumarate
  161. TA174: Leukaemia (chronic lymphocytic, first line) - rituximab
  162. NICE issues updated Type 2 diabetes guidelines
  163. TA172: Head and neck cancer (squamous cell carcinoma) - cetuximab
  164. TA171: Multiple myeloma - lenalidomide
  165. TA169: Sunitinib for the first-line treatment of advanced and/or metastatic renal cell carcinoma
  166. TA36: Rheumatoid arthritis - etanercept and infliximab (Partially replaced by TA130)
  167. TA168: Influenza - zanamivir, amantadine and oseltamivir (review)
  168. CADTH issues guidelines in the management of neuropathic pain
  169. TA163: Ulcerative colitis (acute exacerbations) - infliximab
  170. TA162: Lung cancer (non-small-cell) - erlotinib
  171. TA160: Osteoporosis - primary prevention
  172. TA161: Osteoporosis - secondary prevention including strontium ranelate
  173. Autologous Progenitor Cell Therapy for the Treatment of Ischemic Heart Disease
  174. NICE Issues Guidance on Two Injectable AMD Products Approved by the FDA
  175. NICE Issues Technology Appraisals on Two Oral Hep B Products Approved by the FDA
  176. NICE issues guidance on sequential use of anti-TNFs
  177. Cognitive Rehabilitation for Traumatic Brain Injury in Adults
  178. Pharmacogenomics-Based Treatment of Helicobacter pylori Infection
  179. CYP2D6 Pharmacogenomics of Tamoxifen Treatment
  180. Off-Label Uses of Sorafenib and Sunitinib